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How do we get these numbers?

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23andMe is a registered trademark of 23andMe, Inc. The use of the name and logo are for compatibility information only and does not imply approval or endorsement of Sequencing.com by 23andMe, Inc.

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Working directly with CLIA-certified labs for clinical-grade 30x Sequencing.

Meet The Families In Need

In honor of Rare Disease Day, we invite you to be part of a special initiative:
For every 50 Rare Disease Day WGS Special Bundles ordered, we pledge to donate a bundle to a family grappling with unresolved health mysteries. These families in need stand to gain invaluable insights from genome sequencing, offering them a beacon of hope in their search for answers.

Valerie

Madyn

Jonathan

From Our Founder’s Heart: Dr. Brandon Colby's Story

Dr. Brandon Colby, founder of Sequencing.com, navigated through a challenging childhood plagued by a mysterious health condition—extensive blistering on his feet and hands, with no diagnosis in sight despite countless medical consultations and tests. His significant discovery was made possible by merging whole genome sequencing with the innovative Next-Gen Disease Screen (NGDS), a combination beyond the capability of any other existing test. This powerful approach finally uncovered the genetic culprit: a mutation in the KRT14 gene. 

This breakthrough not only provided Dr. Colby with much-needed clarity but also allowed him and his wife to make informed decisions about their family's future, understanding the implications of their genetic makeup. Dr. Colby's experience highlights the transformative impact of NGDS, showcasing its potential to replace fear and uncertainty with empowerment and precise genetic knowledge.

Meet The Families In Need

In honor of Rare Disease Day, we invite you to be part of a special initiative:
For every 50 Rare Disease Day WGS Special Bundles ordered, we pledge to donate a bundle to a family grappling with unresolved health mysteries. These families in need stand to gain invaluable insights from genome sequencing, offering them a beacon of hope in their search for answers.

Valerie

View Story

Madyn

View Story

Jonathan

View Story

From our founder’s heart: Dr. Brandon Colby's story

extensive blistering on his feet and hands, with no diagnosis in sight despite countless medical consultations and tests. His significant discovery was made possible by merging whole genome sequencing with the innovative Next-Gen Disease Screen (NGDS), a combination beyond the capability of any other existing test. This powerful approach finally uncovered the genetic culprit: a mutation in the KRT14 gene. 

This breakthrough not only provided Dr. Colby with much-needed clarity but also allowed him and his wife to make informed decisions about their family's future, understanding the implications of their genetic makeup. Dr. Colby's experience highlights the transformative impact of NGDS, showcasing its potential to replace fear and uncertainty with empowerment and precise genetic knowledge.

Dr. Brandon Colby, founder of Sequencing.com, navigated through a challenging childhood plagued by a mysterious health condition—

Dr. Brandon Colby, founder of Sequencing.com, navigated through a challenging childhood plagued by a mysterious health condition—extensive blistering on his feet and hands, with no diagnosis in sight despite countless medical consultations and tests. His significant discovery was made possible by merging whole genome sequencing with the innovative Next-Gen Disease Screen (NGDS), a combination beyond the capability of any other existing test. This powerful approach finally uncovered the genetic culprit: a mutation in the KRT14 gene. 

This breakthrough not only provided Dr. Colby with much-needed clarity but also allowed him and his wife to make informed decisions about their family's future, understanding the implications of their genetic makeup. Dr. Colby's experience highlights the transformative impact of NGDS, showcasing its potential to replace fear and uncertainty with empowerment and precise genetic knowledge.

From our founder’s heart: Dr. Brandon Colby's story

Ginny

Inga

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Andrew

Kenzie

Andrew

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Kenzie

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Alyssa

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Meet The Families In Need

In honor of Rare Disease Day, we invite you to be part of a special initiative:
For every 50 Rare Disease Day WGS Special Bundles ordered, we pledge to donate a bundle to a family grappling with unresolved health mysteries. These families in need stand to gain invaluable insights from genome sequencing, offering them a beacon of hope in their search for answers.

Valerie

Madyn

Jonathan

Ginny

Andrew

Kenzie

Alyssa

Meet The Families In Need

In honor of Rare Disease Day, we invite you to be part of a special initiative:
For every 50 Rare Disease Day WGS Special Bundles ordered, we pledge to donate a bundle to a family grappling with unresolved health mysteries. These families in need stand to gain invaluable insights from genome sequencing, offering them a beacon of hope in their search for answers.

Valerie

View Story

Madyn

View Story

Jonathan

View Story

Inga

View Story

Andrew

View Story

Kenzie

View Story

Made Possible With Whole Genome Sequencing

DNA tests from 23andMe, AncestryDNA, and most other companies use older technology that produces data on a very small subset of the total genome.
 
Whole genome sequencing is an entirely different class of technology that tests every letter of your DNA, including all ~30,000 genes and all chromosomes end-to-end.

0.1%

100%

Of Your Genome

Of Your Genome

Order Special Sequencing BundleOrder Special Sequencing Bundle

Free Shipping + HSA/FSA Eligible

Alyssa

Order Special Sequencing Bundle

5 Health Reports Included 

Sequencing Includes

Whole Genome Sequencing

Carrier screening

Connective Tissue Disorders

Autoimmune Disorders

Sequencing

Cost on your own

$2,500

$350

$1450

$1450

$6740

*

N/A

$990

$389

Screen For 15,000+ Conditions

Development Disorders

More insights. Lower cost. Total DNA clarity.

Get Whole Genome Sequencing with 15,000+ condition screening, health reports, and lifetime data storage—all for one price. No other company offers this much insight and lifelong access in one product.

* No other company on the market provides screening for 15k+ conditions in one product to consumers for any price.

Buy Now

More insights. Lower cost. Total DNA clarity.

Whole Genome Sequencing

Connective Tissue Disorders

Autoimmune Disorders

Carrier Screening

Sequencing Includes

Sequencing

Cost on your own

$350

$1450

$1450

$990

N/A

$2,500

$6740

*

$389

Screen For 15,000+ Conditions

* No other company on the market provides screening for 15k+ conditions in one product to consumers for any price.

Based on Blueprint Genetics, Invitae, Natera, and Prevention Genetics as of March 2025.

Development Disorders

Buy Now

Based on Blueprint Genetics, Invitae, Natera, and Prevention Genetics as of March 2025.

Made possible with Whole Genome Sequencing

DNA tests from 23andMe, AncestryDNA, and most other companies use older technology that produces data on a very small subset of the total genome.
 
Whole genome sequencing is an entirely different class of technology that tests every letter of your DNA, including all ~30,000 genes and all chromosomes end-to-end.

0.1%

100%

Of Your Genome

Of Your Genome

Sequencing.com analyzes your entire genome to screen for 15,000+ diseases, conditions, traits, and medication reactions, covering almost every disease with a known genetic component.

Made Possible With Whole Genome Sequencing

DNA tests from 23andMe, AncestryDNA, and most other companies use older technology that produces data on a very small subset of the total genome.
 
Whole genome sequencing is an entirely different class of technology that tests every letter of your DNA, including all ~30,000 genes and all chromosomes end-to-end.

0.1%

100%

Of Your Genome

Of Your Genome

Screen for more than 15,000 conditions

Sequencing.com analyzes your entire genome to screen for 15,000+ diseases, conditions, traits, and medication reactions, covering almost every disease with a known genetic component.

What people are saying

Lillian L.

"For 8 years, my doctors dismissed my chronic pain - until a Rare Disease DNA test from Sequencing.com finally led to the diagnosis I’d been searching for."

Katherine F.

"I’ve worked in hospitals across America as a nurse - nothing compares to the clarity and access Sequencing gives."

Tia W.

"Being able to self-order genetic testing for Ehlers-Danlos Syndrome changed everything, Sequencing empowered me to rule out other hypermobile conditions and finally feel in charge of my health."

Katherine F.

"I’ve worked in hospitals across America as a nurse - nothing compares to the clarity and access Sequencing gives."

Lillian L.

"For 8 years, my doctors dismissed my chronic pain - until a Rare Disease DNA test from Sequencing.com finally led to the diagnosis I’d been searching for."

Tia W.

"Being able to self-order genetic testing for Ehlers-Danlos Syndrome changed everything, Sequencing empowered me to rule out other hypermobile conditions and finally feel in charge of my health."

What people are saying

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This Rare Disease Month, take a step toward clarity with whole genome sequencing, screening for 15,000+ genetic conditions, medication reactions, and inherited risks.

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Answers today. Health intelligence for life.

This Rare Disease Month, take a step toward clarity with whole genome sequencing, screening for 15,000+ genetic conditions, medication reactions, and inherited risks.

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Health Screening WGS Bundle
Have a question?
Whole Genome Sequencing

Choose Your Sequencing Bundle

  • All-in-one bundle includes your genome data, health analyses, and reports
  • Tests ~100% of your genome  

    We sequence and analyze your entire genome, reading all ~3 billion letters of your DNA across every gene and chromosome. You also have secure access to download your raw genome files and reports at no extra cost.

    The files are provided in standard genomics formats (FASTQ, BAM, and VCF), giving you complete ownership of your data and results.

  • All ~30,000 genes and all chromosomes sequenced
  • Clinical-grade (30x sequencing depth)
  • Easy, at-home DNA collection using a gentle mouth swab
  • Privacy Forever™ data protection  

    Privacy Forever™ means your DNA data is never sold, shared, or used for advertising — ever. We are HIPAA-compliant and certified under the US-EU-Swiss Data Privacy Framework.

    You retain full ownership and control of your data and can request deletion at any time.

1 Choose Your Bundle

Standard
$389 $559 30% Off
Professional
$589 $1,359 50% Off

2 Choose Your Lab Processing Speed

Regular 7–8 weeks Free
Expedited 4–6 weeks +$50
Ultra Rapid 2–3 weeks +$200
Standard Bundle — Regular Lab Processing
Total
$389 Free Worldwide Shipping
Buy Now → ✓ HSA / FSA Eligible
Which conditions are screened for?

Every kit bundle includes our Next Gen Disease Screen, which analyzes 15,000+ rare diseases and pharmacogenetic (medication response) markers. Search the full, up-to-date list here: Browse covered conditions.

Do you screen for all types of EDS?

Our whole genome sequencing service provides screening for all types of Ehlers-Danlos Syndrome (EDS) that are known to be associated with genetic variants (mutations) in a gene.

Please note that for hypermobile type of EDS (hEDS), there is limited information that can be provided at this time. Recent research did identify an association between the Klk15 gene and hEDS but this is still a preliminary association.

Some people who suspect hEDS do use our service to obtain information about whether they have a change in a gene that may put them at risk of another type of Ehlers-Danlos Syndrome.

What's included in a kit bundle?

Every Sequencing kit bundle includes 30x whole genome sequencing of all ~30,000 genes and all chromosomes end-to-end as well as:

  • Free worldwide shipping of our swab-based DNA collection kit
  • Whole genome sequencing (30x WGS) performed in a US-based clinical laboratory
  • Comprehensive analysis of more than 15,000 conditions and medication reactions
  • A Summary Report of the results downloadable as PDF
  • Additional AI Reports downloadable as PDF (each bundle includes a different set)
  • Your choice of any 2 additional AI Reports after sequencing completes
  • Privacy Forever protection of your data — HIPAA and US-EU-Swiss Data Privacy Framework compliant

Additional Features

Our Marketplace provides optional DNA reports (nutrition, sleep, genealogy, etc). We also offer Genome Plans for monthly updates and AI Chat access.

Is a subscription required?

A subscription is not required.

We offer an optional subscription service called Genome Plans, which updates your analysis and reports monthly and includes SequencingAI features.

Every kit includes either 1 month or 1 year of Premium Genome Plan. You can downgrade to the Free Plan anytime while keeping full access to your data and included reports.

The subscription is only for ongoing updates and extra features. Even without it, you retain lifetime access to your data and included reports.

Health Areas

As low as $36 a month

Our Difference

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Our Privacy Forever™ policy is our promise
to you:

  • You own your DNA data. We keep it secure and confidential. We never sell it to anyone.
  • Your data is never shared with research organizations, pharmaceutical companies, government agencies, or insurance providers.
  • We’re HIPAA compliant and certified under the US-EU-UK-Swiss Data Privacy Framework.
  • You can access, download, or permanently delete your data and reports at any time.
  • After sequencing is complete, your DNA sample and collection kit are destroyed.

Our only loyalty is to you.

Health Screening WGS Bundle — Mobile

1 Choose Your Bundle

Standard
$389 $559 30% Off
Professional
$589 $1,359 50% Off

2 Choose Your Clinical Lab Turnaround Speed

Regular 7–8 weeks Free
Expedited 4–6 weeks +$50
Ultra Rapid 2–3 weeks +$200
Standard Bundle — Regular Lab Processing
Total
$389 Free Worldwide Shipping
Buy Now → ✓ HSA / FSA Eligible
Health Areas

Whole Genome Sequencing

Choose Your Sequencing Bundle

All-in-one bundle to know your preventable health analyses and reports
Tests 100% of your genome — 
All 22,000 genes and all chromosomes sequenced
Chromosomal DNA sequencing (only available in genome screening)
Easy at-home DNA collection using a gentle mouth swab
"Privacy Forever" data protection —

Learn More

Learn More

We sequence and analyze your entire genome, reading all ~3 billion letters of your DNA across every gene and chromosome. You also have secure access to download your raw genome files and reports at no extra cost. The files are provided in standard genomics formats (FASTQ, BAM, and VCF), giving you complete ownership of your data and results.

Our Privacy Forever™ policy is our promise
to you:

  • You own your DNA data. We keep it secure and confidential. We never sell it to anyone.
  • Your data is never shared with research organizations, pharmaceutical companies, government agencies, or insurance providers.
  • We’re HIPAA compliant and certified under the US-EU-UK-Swiss Data Privacy Framework.
  • You can access, download, or permanently delete your data and reports at any time.
  • After sequencing is complete, your DNA sample and collection kit are destroyed.

Our only loyalty is to you.

As low as $36 a month

Buy Now

Find the Missing Piece in Your Health Journey

End the guesswork. Discover what your DNA may reveal about your health and take the next step toward clarity, confidence, and control.

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End the guesswork. Discover what your DNA may reveal about your health and take the next step toward clarity, confidence,
and control.

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