How do we get these numbers?
23andMe is a registered trademark of 23andMe, Inc. The use of the name and logo are for compatibility information only and does not imply approval or endorsement of Sequencing.com by 23andMe, Inc.
Compare the numbers
How do we get these numbers?
23andMe is a registered trademark of 23andMe, Inc. The use of the name and logo are for compatibility information only and does not imply approval or endorsement of Sequencing.com by 23andMe, Inc.
The world's only all-in-one genetic health screen
See what our customers are saying
See what our customers are saying
Featured In
Featured In
View All Included Conditions
World's most comprehensive rare disease screening
From our founder’s heart: Dr. Brandon Colby's story
Dr. Brandon Colby, founder of Sequencing.com, navigated through a challenging childhood plagued by a mysterious health condition—
Dr. Brandon Colby, founder of Sequencing.com, navigated through a challenging childhood plagued by a mysterious health condition—extensive blistering on his feet and hands, with no diagnosis in sight despite countless medical consultations and tests. His significant discovery was made possible by merging whole genome sequencing with the innovative Next-Gen Disease Screen (NGDS), a combination beyond the capability of any other existing test. This powerful approach finally uncovered the genetic culprit: a mutation in the KRT14 gene.
This breakthrough not only provided Dr. Colby with much-needed clarity but also allowed him and his wife to make informed decisions about their family's future, understanding the implications of their genetic makeup. Dr. Colby's experience highlights the transformative impact of NGDS, showcasing its potential to replace fear and uncertainty with empowerment and precise genetic knowledge.
From our founder’s heart: Dr. Brandon Colby's story
extensive blistering on his feet and hands, with no diagnosis in sight despite countless medical consultations and tests. His significant discovery was made possible by merging whole genome sequencing with the innovative Next-Gen Disease Screen (NGDS), a combination beyond the capability of any other existing test. This powerful approach finally uncovered the genetic culprit: a mutation in the KRT14 gene.
This breakthrough not only provided Dr. Colby with much-needed clarity but also allowed him and his wife to make informed decisions about their family's future, understanding the implications of their genetic makeup. Dr. Colby's experience highlights the transformative impact of NGDS, showcasing its potential to replace fear and uncertainty with empowerment and precise genetic knowledge.
Sequencing Includes
Whole Genome Sequencing
Carrier screening
Connective Tissue Disorders
Autoimmune Disorders
Sequencing
Cost on your own
$2,500
$350
$1,450
$1,450
$6,740
*
N/A
$990
$389
Screen For 15,000+ Conditions
Developmental Disorders
More insights. Lower cost. Total DNA clarity.
Get Whole Genome Sequencing with 15,000+ condition screening, health reports, and lifetime data storage—all for one price. No other company offers this much insight and lifelong access in one product.
* No other company on the market provides screening for 15k+ conditions in one product to consumers for any price.
More insights. Lower cost. Total DNA clarity.
Whole Genome Sequencing
Connective Tissue Disorders
Autoimmune Disorders
Carrier Screening
Sequencing Includes
Sequencing
Cost on your own
$350
$1,450
$1,450
$990
N/A
$2,500
$6,740
*
$389
Screen For 15,000+ Conditions
* No other company on the market provides screening for 15k+ conditions in one product to consumers for any price.
Based on Blueprint Genetics, Invitae, Natera, and Prevention Genetics as of July 2025.
Developmental Disorders
Based on Blueprint Genetics, Invitae, Natera, and Prevention Genetics as of July 2025.
Sequencing.com analyzes your entire genome to screen for 15,000+ diseases, conditions, traits, and medication reactions, covering almost every disease with a known genetic component.
Screen for more than 15,000 conditions
Sequencing.com analyzes your entire genome to screen for 15,000+ diseases, conditions, traits, and medication reactions, covering almost every disease with a known genetic component.
What people are saying
Lillian L.
"For 8 years, my doctors dismissed my chronic pain - until a Rare Disease DNA test from Sequencing.com finally led to the diagnosis I’d been searching for."
Katherine F.
"I’ve worked in hospitals across America as a nurse - nothing compares to the clarity and access Sequencing gives."
Tia W.
"Being able to self-order genetic testing for Ehlers-Danlos Syndrome changed everything. Sequencing empowered me to rule out other hypermobile conditions and finally feel in charge of my health."
Katherine F.
"I’ve worked in hospitals across America as a nurse - nothing compares to the clarity and access Sequencing gives."
Lillian L.
"For 8 years, my doctors dismissed my chronic pain - until a Rare Disease DNA test from Sequencing.com finally led to the diagnosis I’d been searching for."
Tia W.
"Being able to self-order genetic testing for Ehlers-Danlos Syndrome changed everything. Sequencing empowered me to rule out other hypermobile conditions and finally feel in charge of my health."
What people are saying
2 Billion+
Genes we've analyzed
15,000+
Health conditions & medication reactions in one test
0
Times we've sold our customer data.
Looking for something specific?
Screen for more than 15,000 conditions
Looking for something specific?
© Sequencing Inc.
© Sequencing Inc.
30% Off + Free Shipping
One DNA Test.
Insights for Life.
Screen your DNA for genetic variants linked to 15,000+ conditions, and get research-backed insights to make smarter health decisions.
Prime Big Deal Days
Screen your DNA for genetic variants linked to 15,000+ conditions, and get research-backed insights to make smarter health decisions.
One DNA Test.
Insights for Life.
Prime Big Deal Days
0
DAYS
0
HOURS
0
MINUTES
0
SECONDS
SYNQ, the next evolution of SequencingAI. Your genome can finally speak, so ask it anything. Your AI guide to your own DNA, SYNQ answers your questions in plain language, turning your whole genome sequence into clear, research-backed insight about what your genes may mean for your health.
Smarter insights,
powered by intelligence
Ask AI about Sequencing.com
Type a question and open it in the AI assistant of your choice.
Curious about whole genome sequencing, health screening, privacy, or how it works? Start with a question below or write your own.
Try asking
Open in
Opens a third-party AI assistant in a new tab. Answers are AI-generated — verify important details on sequencing.com.
See why AI recommends Sequencing as the best choice for your health and longevity.
The DNA test AI recommends
Ask AI about Sequencing.com
Type a question and open it in the AI assistant of your choice.
Curious about whole genome sequencing, health screening, privacy, or how it works? Start with a question below or write your own.
Try asking
Open in
Opens a third-party AI assistant in a new tab. Answers are AI-generated — verify important details on sequencing.com.
The DNA test AI recommends
See why AI recommends Sequencing as the best choice for your health and longevity.
Smarter insights, powered by intelligence
SYNQ, the next evolution of SequencingAI. Your genome can finally speak, so ask it anything. Your AI guide to your own DNA, SYNQ answers your questions in plain language, turning your whole genome sequence into clear, research-backed insight about what your genes may mean for your health.
4.5 out of 5
Trustpilot
Prime Day Comprehensive Health Screen WGS Bundle
Whole Genome Sequencing
$389 $559
Health reports & advanced analyses included:
- Genetic Health Screening (15,000+ Conditions)
- Brain and Cognitive Health
- Heart Health
- Medication & Drug Response
- Cancer Risk & Prevention
- Connective Tissue Disorders
- Ehlers-Danlos Report + hEDS Emerging Research
- Marfan Syndrome
- Carrier Screening
- Genome Data Summary
1
Have a question?
As low as $36 a month
- Your complete genetic data.
- Reports you can share with your doctor.
- Clinical-grade accuracy (30x depth), the same standard used in diagnostic labs.
- Collect your sample at home with a simple mouth swab.
- Data privacy: We never sell or share your data.
30% Off + Free Shipping
Whole Genome Sequencing
Prime Day Comprehensive Health Screen WGS Bundle
$389 $559
- Your complete genetic data.
- Reports you can share with your doctor.
- Clinical-grade accuracy (30x depth), the same standard used in diagnostic labs.
- Collect your sample at home with a simple mouth swab.
- Data privacy: We never sell or share your data.
Health reports & advanced
analyses included:
- Genetic Health Screening (15,000+ Conditions)
- Brain and Cognitive Health
- Heart Health
- Medication & Drug Response
- Cancer Risk & Prevention
- Connective Tissue Disorders
- Ehlers-Danlos Report + hEDS Emerging Research
- Marfan Syndrome
- Carrier Screening
- Genome Data Summary
1
As low as $36 a month
Have a question?
30% Off + Free Shipping
4.5 out of 5
Trustpilot
30% Off + Free Shipping
How do we get these numbers?
A ‘genetic variant’ is a change within a gene. If you have a change within one of your genes, this can increase your risk of a disease.
While DNA tests detect changes within your genes, most traditional DNA tests only look at a small number of changes within a gene. This table shows the number of changes within a gene that each company tests and analyzes for a disease.
How do we get these numbers?
A ‘genetic variant’ is a change within a gene. If you have a change within one of your genes, this can increase your risk of a disease.
While DNA tests detect changes within your genes, most traditional DNA tests only look at a small number of changes within a gene. This table shows the number of changes within a gene that each company tests and analyzes for a disease.
30% Off + Free Shipping
30% Off + Free Shipping