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How do we get these numbers?
23andMe is a registered trademark of 23andMe, Inc. The use of the name and logo are for compatibility information only and does not imply approval or endorsement of Sequencing.com by 23andMe, Inc.
The World's Most Comprehensive Rare Disease Screening
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Ready To Get Sequenced?
Start by ordering the world’s most comprehensive DNA test kit.
Ready To Get Sequenced?
Start by ordering the world’s most comprehensive DNA test kit.
Obtains data on around 3 billion positions within your genome (100% of your genome). Also includes the ability to download your raw genome data files for no additional fee. This includes FASTQ, BAM and VCFs covering all genetic variations: Single Nucleotide Polymorphisms (SNPs), Insertions and Deletions (INDELs), Structural Variations (SVs), Copy Number Variations (CNVs) and Mitochondrial Heteroplasmy (MITO).
Prime Day Exclusive WGS Bundle
$379 $539
HEALTH AREAS INCLUDED:
Full Access To All Raw Genome Data & Analyzed Data:
3 billion genetic variants
All 30,000 genes sequenced
All chromosomes fully sequenced incl. the mitochondrial & Y chromosomes
100% of your genome
30x genome sequencing
Whole Genome Sequencing
One Month Premium Genome Plan
HSA/FSA
Eligible
25% Off + Extra 5% Off + Free Shipping
As low as $34/month
- Rare Disease Screening
(15,000+ Conditions) - NEW Ehlers-Danlos Report
+ hEDS Emerging Research - Carrier Screening
- Autoimmune Disorders
- Medication & Drug Response
- Musculoskeletal Health
Prime Day Exclusive WGS Bundle
$379 $539
One Month Premium Genome Plan
Whole Genome Sequencing
Full Access To All Raw Genome Data & Analyzed Data:
3 billion genetic variants
All 30,000 genes sequenced
All chromosomes fully sequenced including the mitochondrial & Y chromosomes
100% of your genome
30x genome sequencing depth
HEALTH AREAS INCLUDED:
- Rare Disease Screening (15,000+ Conditions)
- NEW Ehlers-Danlos Report + hEDS Emerging Research
- Carrier Screening
- Autoimmune Disorders
- Medication & Drug Response
- Musculoskeletal Health
HSA/FSA
Eligible
25% Off + Extra 5% Off + Free Shipping
or as low as $34/month
Obtains data on around 3 billion positions within your genome (100% of your genome). Also includes the ability to download your raw genome data files for no additional fee. This includes FASTQ, BAM and VCFs covering all genetic variations: Single Nucleotide Polymorphisms (SNPs), Insertions and Deletions (INDELs), Structural Variations (SVs), Copy Number Variations (CNVs) and Mitochondrial Heteroplasmy (MITO).
World's Most Comprehensive Rare Disease Screening
End the guesswork. Discover what your DNA may reveal about your health and take the next step toward clarity, confidence,
and control.
Meet The Families In Need
In honor of Rare Disease Day, we invite you to be part of a special initiative:
For every 50 Rare Disease Day WGS Special Bundles ordered, we pledge to donate a bundle to a family grappling with unresolved health mysteries. These families in need stand to gain invaluable insights from genome sequencing, offering them a beacon of hope in their search for answers.
From Our Founder’s Heart: Dr. Brandon Colby's Story
Dr. Brandon Colby, founder of Sequencing.com, navigated through a challenging childhood plagued by a mysterious health condition—extensive blistering on his feet and hands, with no diagnosis in sight despite countless medical consultations and tests. His significant discovery was made possible by merging whole genome sequencing with the innovative Next-Gen Disease Screen (NGDS), a combination beyond the capability of any other existing test. This powerful approach finally uncovered the genetic culprit: a mutation in the KRT14 gene.
This breakthrough not only provided Dr. Colby with much-needed clarity but also allowed him and his wife to make informed decisions about their family's future, understanding the implications of their genetic makeup. Dr. Colby's experience highlights the transformative impact of NGDS, showcasing its potential to replace fear and uncertainty with empowerment and precise genetic knowledge.
From Our Founder’s Heart: Dr. Brandon Colby's Story
extensive blistering on his feet and hands, with no diagnosis in sight despite countless medical consultations and tests. His significant discovery was made possible by merging whole genome sequencing with the innovative Next-Gen Disease Screen (NGDS), a combination beyond the capability of any other existing test. This powerful approach finally uncovered the genetic culprit: a mutation in the KRT14 gene.
This breakthrough not only provided Dr. Colby with much-needed clarity but also allowed him and his wife to make informed decisions about their family's future, understanding the implications of their genetic makeup. Dr. Colby's experience highlights the transformative impact of NGDS, showcasing its potential to replace fear and uncertainty with empowerment and precise genetic knowledge.
Dr. Brandon Colby, founder of Sequencing.com, navigated through a challenging childhood plagued by a mysterious health condition—
Dr. Brandon Colby, founder of Sequencing.com, navigated through a challenging childhood plagued by a mysterious health condition—extensive blistering on his feet and hands, with no diagnosis in sight despite countless medical consultations and tests. His significant discovery was made possible by merging whole genome sequencing with the innovative Next-Gen Disease Screen (NGDS), a combination beyond the capability of any other existing test. This powerful approach finally uncovered the genetic culprit: a mutation in the KRT14 gene.
This breakthrough not only provided Dr. Colby with much-needed clarity but also allowed him and his wife to make informed decisions about their family's future, understanding the implications of their genetic makeup. Dr. Colby's experience highlights the transformative impact of NGDS, showcasing its potential to replace fear and uncertainty with empowerment and precise genetic knowledge.
From Our Founder’s Heart: Dr. Brandon Colby's Story
Meet The Families In Need
In honor of Rare Disease Day, we invite you to be part of a special initiative:
For every 50 Rare Disease Day WGS Special Bundles ordered, we pledge to donate a bundle to a family grappling with unresolved health mysteries. These families in need stand to gain invaluable insights from genome sequencing, offering them a beacon of hope in their search for answers.
Made Possible With Whole Genome Sequencing
DNA tests from 23andMe, AncestryDNA, and most other companies use older technology that produces data on a very small subset of the total genome.
Whole genome sequencing is an entirely different class of technology that tests every letter of your DNA, including all ~30,000 genes and all chromosomes end-to-end.
0.1%
100%
Of Your Genome
Of Your Genome
Free Shipping | Lowest Price Of The Year
+
25% Off + Extra 5% Off + Free Shipping Lowest Price Of The Year
End the guesswork. Discover what your DNA may reveal about your health and take the next step toward clarity, confidence, and control.
5 Health Reports Included
Sequencing Includes
Whole Genome Sequencing
Carrier screening
Connective Tissue Disorders
Autoimmune Disorders
Sequencing
Cost on your own
$2,500
$350
$1450
$1450
$6740
*
N/A
$990
$399
Screen For 15,000+ Conditions
Development Disorders
More Insights. Lower Cost. Total DNA Clarity.
Get Whole Genome Sequencing with 15,000+ condition screening, health reports, and lifetime data storage—all for one price. No other company offers this much insight and lifelong access in one product.
* No other company on the market provides screening for 15k+ conditions in one product to consumers for any price.
More Insights. Lower Cost. Total DNA Clarity.
Whole Genome Sequencing
Connective Tissue Disorders
Autoimmune Disorders
Carrier Screening
Sequencing Includes
Sequencing
Cost on your own
$350
$1450
$1450
$990
N/A
$2,500
$6740
*
$399
Screen For 15,000+ Conditions
* No other company on the market provides screening for 15k+ conditions in one product to consumers for any price.
Based on Blueprint Genetics, Invitae, Natera, and Prevention Genetics as of March 2025.
Development Disorders
Based on Blueprint Genetics, Invitae, Natera, and Prevention Genetics as of March 2025.
Made Possible With Whole Genome Sequencing
DNA tests from 23andMe, AncestryDNA, and most other companies use older technology that produces data on a very small subset of the total genome.
Whole genome sequencing is an entirely different class of technology that tests every letter of your DNA, including all ~30,000 genes and all chromosomes end-to-end.
0.1%
100%
Of Your Genome
Of Your Genome
Start Your Journey with Next-Gen Disease Screen
Traditional labs charge thousands of dollars to test for a single disease, and at most, up to 30 diseases. These expensive tests often only scratch the surface of your genes, leaving a wealth of crucial information untouched.
NGDS is here to change that narrative. Analyzing whole genome sequencing data, NGDS provides a straightforward assessment of your genetic risk for more than 15,000 diseases, conditions, traits, and medication reactions. This transformative tool enables you to screen your entire genome for almost every disease with a known genetic component.
Made Possible With Whole Genome Sequencing
DNA tests from 23andMe, AncestryDNA, and most other companies use older technology that produces data on a very small subset of the total genome.
Whole genome sequencing is an entirely different class of technology that tests every letter of your DNA, including all ~30,000 genes and all chromosomes end-to-end.
0.1%
100%
Of Your Genome
Of Your Genome
Start Your Journey with Next-Gen Disease Screen
Traditional labs charge thousands of dollars to test for a single disease, and at most, up to 30 diseases. These expensive tests often only scratch the surface of your genes, leaving a wealth of crucial information untouched.
© 2025 Sequencing.com
© 2025 Sequencing.com
Katherine F.
@katherine.b.fox
"I’ve worked in hospitals across America as a nurse - nothing compares to the clarity and access Sequencing gives."
Lillian L.
@chunka.munka
"For 8 years, my doctors dismissed my chronic pain - until a Rare Disease DNA test from Sequencing.com finally led to the diagnosis I’d been searching for."
Tia W.
@tortillawilson
"Being able to self-order genetic testing for Ehlers-Danlos Syndrome changed everything, Sequencing empowered me to rule out other hypermobile conditions and finally feel in charge of my health."
What People Are Saying
25% Off + Extra 5% Off
Find the Missing Piece in Your Health Journey
What People Are Saying
Lillian L.
@chunka.munka
"For 8 years, my doctors dismissed my chronic pain - until a Rare Disease DNA test from Sequencing.com finally led to the diagnosis I’d been searching for."
Katherine F.
@katherine.b.fox
"I’ve worked in hospitals across America as a nurse - nothing compares to the clarity and access Sequencing gives."
Tia W.
@tortillawilson
"Being able to self-order genetic testing for Ehlers-Danlos Syndrome changed everything, Sequencing empowered me to rule out other hypermobile conditions and finally feel in charge of my health."
